College football odds, lines, bets, top predictions for Week 12, 2021: Proven model picks Michigan, Pittsburgh

No. 8 Notre Dame has quietly hung around in the College Football Playoff discussion following its loss to then-No. 7 Cincinnati in early October. The Fighting Irish have bounced back with five consecutive wins, including a 28-3 victory at Virginia last week. They are set to host Georgia Tech on Saturday as part of the Week 12 college football schedule. Notre Dame is a 17-point favorite in the latest Week 12 college football odds at Caesars Sportsbook.

The Fighting Irish have won their last five games by an average of 16.2 points. Will they cover the spread against Georgia Tech on Saturday? And which other college football lines should you be targeting on Friday and Saturday? Before making any Week 12 college football picks, be sure to see the latest college football predictions and betting advice from SportsLine’s proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 12 of the 2021 season on a 36-23 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest Week 12 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.

Top Week 12 college football predictions

One of the top college football picks the model is recommending for Week 12: No. 18 Pittsburgh (-14.5) covers at home against Virginia in a 3:30 p.m. ET ACC matchup. The Panthers have a chance to clinch their berth in the ACC title game with a win on Saturday afternoon. They have bounced…


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